Rapamycin (GMP), CAS 53123-88-9

Product Description: Rapamycin (Sirolimus) (GMP) is Rapamycin (HY-10219) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Rapamycin is a potent and specific mTOR inhibitor[1][2][3].

Applications: Cancer-Kinase/protease

Formula: C51H79NO13

References: [1]Lee KW, et al. Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway. Stem Cells Dev. 2010 Apr;19(4):557-68./[2]Martin KA, et al. Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling. J Biol Chem. 2007 Dec 7;282(49):36112-20./[3]Ogawa T, et al. Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells. Biochem Biophys Res Commun. 1998 Aug 10;249(1):226-30.

CAS Number: 53123-88-9

Molecular Weight: 914.17

Compound Purity: 99.8

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: mTOR

• SKU: MEXHY-10219G-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10219G-50
• Package Unit: 50 mg
• Quantity Unit: STK