Rezivertinib, CAS 1835667-12-3

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[2-[2-(dimethylamino)ethoxy]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide

Purity: ≥98%

Formula Markup: C27H30N6O3

Formula Weight: 486.56574

CAS Number: 1835667-12-3

Notes: An inhibitor of mutant EGFR; selectively inhibits the proliferation of mutant-EGFR-containing PC-9, HCC827, and H1975 cells (GI50s = 13.3, 6.8, and 22 nM, respectively) over wild-type EGFR-containing A431 cells (GI50 = >1,000 nM); increases survival in an H1975 brain orthotopic rat model

• SKU: CAY42537-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42537-1
• Package Unit: 1 mg
• Quantity Unit: STK