SB-699551 (hydrochloride)

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 3-cyclopentyl-N-(2-(dimethylamino)ethyl)-N-((4'-((phenethylamino)methyl)-[1,1'-biphenyl]-4-yl)methyl)propanamide, hydrochloride

Purity: ≥95%

Formula Markup: C34H45N3O / XHCl

Formula Weight: 511.754

Notes: A 5-HT5A antagonist (Ki = 6.31 nM); selective for 5-HT5A over a panel of 14 other receptors (Kis = >315 nM for all) but does inhibit SERT (Ki = 25.12 nM); decreases sphere formation in PDX breast cancer cells (IC50 = 596 nM); decreases tumor volume in combination with docetaxel in a PDX mouse model of breast cancer; inhibits cued fear conditioning in mice (ED50 = 25.4 mg/kg)

• SKU: CAY42517-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42517-25
• Package Unit: 25 mg
• Quantity Unit: STK