SKF 89976A (hydrochloride), CAS 85375-15-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-(4,4-diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid, monohydrochloride

Purity: ≥98%

Formula Markup: C22H25NO2 / HCl

Formula Weight: 371.90008

CAS Number: 85375-15-1

Notes: A GAT1 inhibitor (IC50s = 0.13 and 0.64 µM for the human and rat transporters, respectively); selective for GAT1 over rat GAT2, human GAT3, and human BGT3 (IC50s = 550, 944, and 7,210 µM, respectively); inhibits GABA uptake in rat synaptosome preparations (IC50 = 341 nM); inhibits DMCM-induced seizures in mice (ED50 = 3.1 mg/kg)

• SKU: CAY42449-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42449-50
• Package Unit: 50 mg
• Quantity Unit: STK