SKL2001 (GMP), CAS 909089-13-0

Product Description: SKL2001 (GMP) is SKL2001 (HY-101085) produced by using GMP guidelines. SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction[1].

Formula: C14H14N4O3

References: [1]Gwak J, et al. Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation. ell Res. 2012 Jan;22(1):237-47./[2]Ohashi W, et al. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1342-1348.

CAS Number: 909089-13-0

Molecular Weight: 286.29

Research Area: Cancer

Target: Wnt;β-catenin

• SKU: MEXHY-101085G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101085G-0
• Package Unit: Get quote
• Quantity Unit: STK