Talarozole, CAS 201410-53-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl]-2-benzothiazolamine

Purity: ≥95%

Formula Markup: C21H23N5S

Formula Weight: 377.50702

CAS Number: 201410-53-9

Notes: A CYP26 inhibitor (IC50 = 0.004 µM); selective for CYP26 over CYP2A1, CYP2C11, CYP17, and CYP19 (IC50s = 9.1, 7.2, 2.6, and 1.3 µM, respectively); increases the levels of all-trans retinoic acid in plasma, skin, liver, fat, kidneys, and spleen in rats at 2.5 mg/kg; inhibits estrogen-induced vaginal keratinization in ovariectomized rats (ED50 = 1 mg/kg), an effect that can be reversed by AGN 193109; increases pinnal epidermal thickness and tail epidermal orthokeratosis percentage in mice from 0.6-2.6 mg/kg

• SKU: CAY42372-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42372-10
• Package Unit: 10 mg
• Quantity Unit: STK