TM2-115, CAS 1197196-47-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-7-(phenylmethoxy)-4-quinazolinamine

Purity: ≥98%

Formula Markup: C28H38N6O2

Formula Weight: 490.652

CAS Number: 1197196-47-6

Notes: An inhibitor of P. falciparum HMT (IC50 = 43 nM); selective for P. falciparum HMT over human G9a (IC50 = >1,000 nM); decreases H3K4me3 in P. falciparum at 1 µM; active against chloroquine-resistant and -sensitive strains of P. falciparum (IC50s = 100 and 116 nM, respectively); decreases parasite levels in P. falciparum-infected isolated human erythrocytes at 1 µM; reduces parasitemia in P. berghei-infected mice at 40 mg/kg

• SKU: CAY42901-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42901-25
• Package Unit: 25 mg
• Quantity Unit: STK