Product Description: Vorinostat (GMP) is a GMP grade Vorinosta (HY-10221). GMP-grade small molecules can be used as auxiliary agents in cell therapy. Vorinostat is a potent, orally available HDAC1, HDAC2, HDAC3 (Class I), HDAC6 and Inhibitors of HDAC7 (Class II) and Class IV (HDAC11)[1].
Formula: C14H20N2O3
References: [1]Hrzenjak A, et al. Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo. Mol Cancer. 2010 Mar 4;9:49.
CAS Number: 149647-78-9
Molecular Weight: 264.32
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: HDAC