Ac-IETD-AFC, CAS 211990-57-7

Exclusive Spring Savings: Up to 20% on selected MCE Products: Screening Libraries (20% off); Recombinant Proteins, MCE Kits, Antibodies, Dyes (15% off); Reference Standard Compounds, siRNA Products (10% off); Bulk Sizes & Custom Synthesis (10% off); PLUS: Get a free Signal Pathway poster with every order! These special prices are already discounted – no additional discounts can be applied during the promotion period. Hurry – this limited-time offer ends May 31, 2025!

Product Description: Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B[1].

Formula: C31H38F3N5O12

References: [1][1]Kazimierz Weglarczyk, et al. Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus. Infect Immun. 2004 May;72(5):2590-7. /[2]Przemysław Reszka, et al. Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem. 2010 Jan;5(1):103-17.

CAS Number: 211990-57-7

Molecular Weight: 729.65

Compound Purity: 99.91

Research Area: Others

Solubility: DMSO : 125 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic)

Target: Caspase

• SKU: MEXHY-P1169-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P1169-25
• Package Unit: 25 mg
• Quantity Unit: STK