Product Description: Gallein is a Gβγ subunit signaling inhibitor that can interfere with the interaction between Gβγ subunit and PI3Kγ, regulate platelet function, and exhibit anti-tumor activity[1][3].
Applications: Cancer-programmed cell death
Formula: C20H12O7
References: [1]Sanz G, et al, Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30;10(1):541. /[2]Kuroyanagi G, Hioki T, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Gallein increases the fibroblast growth factor 2-elicited osteoprotegerin synthesis in osteoblasts. Biochim Biophys Acta Gen Subj. 2024 Aug;1868(8):130635. /[3]Alarabi AB, et al. The G-protein βγ subunits regulate platelet function. Life Sci. 2020 Dec 1;262:118481.
CAS Number: 2103-64-2
Molecular Weight: 364.31
Compound Purity: 98.0
Research Area: Cancer
Solubility: DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 80°C)
Target: PI3K
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