Product Description: H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity[1].
Formula: C14H23Cl2N7O4
References: [1]Hortin G L, et al. Macromolecular chromogenic substrates for measuring proteinase activity[J]. Clinical chemistry, 2001, 47(2): 215-222.
CAS Number: 125455-61-0
Molecular Weight: 424.28
Research Area: Others
Target: Fluorescent Dye