Product Description: KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg2+ transport across the mitochondrial membrane in the early phases of a cellular model[1].
Formula: C30H28N3O6+
References: [1]Shindo Y, et al. Newly developed Mg<sup>2+</sup>-selective fluorescent probe enables visualization of Mg<sup>2+</sup> dynamics in mitochondria. PLoS One. 2011;6(8):e23684.