Product Description: L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2•−) and identify Nox inhibitors[1].
Applications: COVID-19-immunoregulation
Formula: C13H8ClN4NaO2
References: [1]Zielonka J, et al. On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation. Free Radic Biol Med. 2013;65:1310-1314./[2]Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47(6):760-766.
CAS Number: 143556-24-5
Molecular Weight: 310.67
Compound Purity: 99.63
Research Area: Inflammation/Immunology
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Reactive Oxygen Species