Product Description: MAT2A inhibitor 6 (Compound 3N-h) is a specific MAT2A inhibitor with oral activity and yellow fluorescence (IC50=26 nM), capable of visualizing MAT2A both in vitro and in vivo (λex = 430 nm, λem = 585 nm). MAT2A inhibitor 6 can induce apoptosis and has anticancer activity, which can be used in cancer research[1].
Applications: Cancer-programmed cell death
Formula: C24H19F2N5O3
References: [1]Wang Z, et al. Computer-aided design of a fluorescent MAT2A inhibitor for visualized cancer synthetic lethality. Bioorg Chem. 2024 Sep;150:107582.
CAS Number: 2447686-21-5
Molecular Weight: 463.44
Research Area: Cancer
Target: Apoptosis;Fluorescent Dye;Methionine Adenosyltransferase (MAT)