Product Description: Suc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays[1][2][3].
Formula: C29H32N4O8
References: [1]Farach HA Jr, et al. Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm. J Biol Chem. 1987 Apr 25;262(12):5483-7./[2]Pinto MR, et al. Chymotrypsin-like enzymes are involved in sperm penetration through the vitelline coat of Ciona intestinalis egg. Mol Reprod Dev. 1990 Aug;26(4):319-23./[3]Mumford RA, et al. A zinc metalloendopeptidase associated with dog pancreatic membranes. J Biol Chem. 1980 Mar 25;255(6):2227-30.
CAS Number: 71973-79-0
Molecular Weight: 564.59
Compound Purity: 99.89
Research Area: Others
Solubility: DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Fluorescent Dye