Werner Syndrome RecQ Helicase-IN-2, CAS 2869954-51-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(5-hydroxy-6-methyl-4-pyrimidinyl)carbonyl]-1-piperazinyl]-N-[2-methyl-4-(trifluoromethyl)phenyl]-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidine-4(7H)-acetamide

Purity: ≥98%

Formula Markup: C32H34F3N9O5

Formula Weight: 681.7

CAS Number: 2869954-51-6

Notes: An inhibitor of WRN (IC50 = 100 nM); selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 100 and >10,000 nM, respectively); reduces tumor volume in an SW48 mouse xenograft model at 120 mg/kg per day

• SKU: CAY41678-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41678-50
• Package Unit: 50 mg
• Quantity Unit: STK