Werner Syndrome RecQ Helicase-IN-4, CAS 2869954-53-8

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(3-hydroxy-2-pyridinyl)carbonyl]-1-piperazinyl]-N-[2-methyl-4-(trifluoromethyl)phenyl]-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidine-4(7H)-acetamide

Purity: ≥95%

Formula Markup: C32H33F3N8O5

Formula Weight: 666.7

CAS Number: 2869954-53-8

Notes: An inhibitor of WRN (IC50 = 60 nM); selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 70 and >10,000 nM, respectively); reduces tumor volume in an SW48 mouse xenograft model at 240 mg/kg per day

• SKU: CAY41679-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41679-25
• Package Unit: 25 mg
• Quantity Unit: STK