Shelf life (days): 730.0
Formulation: A solution in ethanol
Formal Name: heptadecan-9-yl (Z)-N-(((4-(dimethylamino)butyl)thio)carbonyl)-N-(2-(non-2-en-1-yloxy)-2-oxoethyl)glycinate
Purity: ≥95%
Formula Markup: C37H70N2O5S
Formula Weight: 655.0
CAS Number: 2230647-30-8
Notes: Lipid 2,2(8,8) 4C CH3 is an ionizable cationic lipid (pKa = 6.69).{64990} It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vivo. LNPs containing lipid 2,2(8,8) 4C CH3 and encapsulating siRNA targeting Factor VII decrease plasma Factor VII protein levels by 90% in mice.