Multidrug Resistance Assay Kit (Calcein AM)

Shelf life (days): 365.0

Formula Weight: 0.0

Notes: Cayman's Multidrug Resistance Assay Kit provides a convenient tool for studying the modulation of cellular multidrug resistance (MDR) machinery. The kit employs calcein AM, a cell-permeable nonfluorescent dye, which is cleaved intracellularly to yield the impermeant fluorescent molecule, calcein. This calcein is rapidly excluded from cells expressing the MDR proteins P-gp or MRP, and so functions as a probe for the detection of chemical compounds inhibiting MDR proteins. Propidium iodide is provided as a stain for marking dead or damaged cells. Cyclosporin A, a competitive inhibitor of MDR proteins, and verapamil, a noncompetitive inhibitor, are included as controls.

• SKU: CAY600370-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 600370-1
• Package Unit: 1 Piece
• Quantity Unit: STK
• Application: Flow Cytometry, Fluorescence