Shelf life (days): 730.0
Formulation: A solid
Formal Name: 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4-dimethyl-5-(methyl-d3)-2-hexen-1-yl-6,6,6-d3]-7a-methyl-4H-inden-4-ylidene]ethylidene]-cyclohexanol
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C28H38D6O2
Formula Weight: 418.68412
CAS Number: 1262843-46-8
Notes: 25-hydroxy Vitamin D2-d6 is intended for use as an internal standard for the quantification of 25-hydroxy vitamin D2 (Item No. 12078) by GC- or LC-MS. 25-hydroxy Vitamin D2 is a metabolite of vitamin D2 (Item No. 11791).{57807} It is formed from vitamin D2 by the cytochrome P450 (CYP) isoforms CYP2R1 and CYP27A1, which have 25-hydroxylase activity, and is bound to vitamin D binding protein (DBP) and albumin in the liver, then secreted into the bloodstream.{60080} 25-hydroxy Vitamin D2 is transported to the kidney, where it is preferentially 24-hydroxylated by CYP24A1 to produce 24,25-dihydroxy vitamin D2.{60080} It can also be hydroxylated by CYP27B1 to produce 1,25-dihydroxy vitamin D2.{60080,57807} Serum levels of 25-hydroxy vitamin D2 have been used as a marker of vitamin D status.{57808}
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