Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (8a,9ß,11ß,14ß,16ß,23S,24R)-16,23-epoxy-11,24,25-trihydroxy-dammar-13(17)-en-3-one
Purity: ≥98%
Formula Markup: C30H48O5
Formula Weight: 488.69912
CAS Number: 155521-45-2
Notes: Alisol F is a triterpene that has been found in A. orientale and has anti-inflammatory and hepatoprotective activities.{68163,68162} It reduces levels of inducible nitric oxide synthase (iNOS) and COX-2 and the production of TNF-α, IL-6,and IL-1β in LPS-stimulated RAW 264.7 cells.{68163} Alisol F (20 mg/kg) reduces plasma alanine transaminase (ALT) and aspartate aminotransferase (AST) levels, hepatic fibrosis, and hepatic levels of phosphorylated ERK in a mouse model of LPS/D-galactosamine-induced acute liver injury.{68163,68162}