Shelf life (days): 730.0
Formulation: A solution in methyl acetate
Formal Name: 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl-2,3,4,5,6,7,8-d7)-2H-pyran-2-one
Purity: ≥99% deuterated forms (d1-d7)
Formula Markup: C16H6D7BrO2
Formula Weight: 324.2
Notes: Bromoenol lactone-d7 (BEL-d7) contains seven deuterium atoms at the 2, 3, 4, 5, 6, 7, and 8 positions. It is intended for use as an internal standard for the quantification of BEL by GC- or LC-MS. BEL is a selective, potent, irreversible, mechanism-based inhibitor of phospholipase A2 (iPLA2) with a Ki value of 180 nM.{1631} It also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible inhibitor of chymotrypsin (Ki = 636 nM).{1291,1770}