Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 1,4-butane-1,1,2,2,3,3,4,4-d8-diol, dimethanesulfonate
Purity: ≥99% deuterated forms (d1-d8)
Formula Markup: C6H6D8O6S2
Formula Weight: 254.3
CAS Number: 116653-28-2
Notes: Busulfan-d8 is intended for use as an internal standard for the quantification of busulfan (Item No. 14843) by GC- or LC-MS. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent.{23714} It forms both intra- and interstrand crosslinks on DNA.{23711,23712} In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.{23713}