Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5H-dibenz[b,f]azepine-1,2,3,4,6,7,8,9,10,11-d10-5-carboxamide
Purity: ≥99% deuterated forms (d1-d10)
Formula Markup: C15H2D10N2O
Formula Weight: 246.32926
CAS Number: 132183-78-9
Notes: Carbamazepine-d10 is intended for use as an internal standard for the quantification of carbamazepine by GC- or LC-MS. Carbamazepine is an anticonvulsant.{57509,57510} It reduces the occurrence of seizures in mouse models of tonic-clonic, or maximal electroshock-induced, seizures (ED50s = 15.46 and ~13 mg/kg, respectively). Dietary administration of carbamazepine (0.75% w/w) reduces immobility time in the tail suspension test.{57511} It also attenuates clonidine-induced aggressive behavior in mice.{57514} Formulations containing carbamazepine have been used in the treatment of epilepsy and bipolar disorder.
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