Elvitegravir-d6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 6-[(3-chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic acid-d6

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C23H17ClD6FNO5

Formula Weight: 453.919923

Notes: Elvitegravir-d6 is intended for use as an internal standard for the quantification of elvitegravir (Item No. 17798) by GC- or LC-MS. Elvitegravir is a quinolone antibiotic that inhibits HIV-1 integrase (IC50 = 7.2 nM).{29011} It has antiviral activity against laboratory strains and clinical isolates of HIV-1 (EC50s = 0.1-1.26 nM) in MAGI cells and HIV-2 (EC50s = 0.3-0.9) in peripheral blood mononuclear cells (PBMCs).{29011,42943} Formulations containing elvitegravir have been used in the treatment of HIV infections.

• SKU: CAY28523
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28523-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung