Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (3R,3a'S,4S,4'S,5R,6R,6'R,7'S,7a'S)-4'-(((1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl)oxy)-6-((S)-1-amino-2-hydroxyethyl)-6'-(hydroxymethyl)octahydro-4'H-spiro[pyran-2,2'-[1,3]dioxolo[4,5-c]pyran]-3,4,5,7'-tetraol
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C20H33D4N3O13
Formula Weight: 531.54444
Notes: Hygromycin B-d4 is intended for use as an internal standard for the quantification of hygromycin B (Item No. 14291) by GC- or LC-MS. Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus.{22696,22442} It is active against E. coli (MIC = 150 µg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis.{57702,22697,22695} Hygromycin B has commonly been used in molecular and cell biology applications to select for transformed cells expressing the E. coli hygromycin resistance genes hyg or hph.{22697,22695}
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