Shelf life (days): 1460.0
Formulation: A solution in methanol
Formal Name: (1-(5-hydroxypentyl)-1H-indol-3-yl)-methanone-2’,4’,5’,6’,7’-d5
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C24H18D5NO2
Formula Weight: 362.5
CAS Number: 2748469-26-1
Notes: JWH 018 N-(5-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2', 4', 5', 6', and 7' positions. It is intended for use as an internal standard for the quantification of JWH 018 N-(5-hydroxypentyl) metabolite by GC- or LC-mass spectrometry (MS). JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.{16797} JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-(5-hydroxypentyl) metabolite is a major urinary metabolite of JWH 018, characterized by monohydroxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated.{18291}
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