Shelf life (days): 1460.0
Formulation: A solid
Formal Name: L-Glutamine-2,3,3,4,4-d5
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C5H5D5N2O3
Formula Weight: 151.17488
CAS Number: 14341-78-7
Notes: L-Glutamine-d5 is intended for use as an internal standard for the quantification of L-glutamine (Item No. 23716) by GC- or LC-MS. L-Glutamine is a conditionally essential amino acid involved in many biochemical processes. It is synthesized in vivo by glutamate and ammonia.{41351} It serves as a substrate for glutamine synthetase in neurons for the biosynthesis of the major excitatory and inhibitory neurotransmitters glutamate and GABA.{41350} L-Glutamine decreases adhesion of sickle red blood cells (RBCs) to human umbilical vein endothelial cells (HUVECs) when incubated ex vivo with patient-derived autologous plasma either alone or with LPS.{41352} It has commonly been used in cell culture media. Formulations containing L-glutamine have been used in the treatment of sickle cell disease.