Shelf life (days): 1460.0
Formulation: A solid
Formal Name: L-valine-2,3,4,4,4,4',4',4'-d8
Purity: ≥99% deuterated forms (d1-d8)
Formula Markup: C5H3D8NO2
Formula Weight: 125.19486
CAS Number: 35045-72-8
Notes: L-Valine-d8 is intended for use as an internal standard for the quantification of L-valine (Item No. 38709) by GC- or LC-MS. L-Valine is a branched-chain essential amino acid that is obtained via the diet.{54328} It is considered glucogenic due to its catabolism that ultimately forms succinyl-CoA, which enters the citric acid cycle.{45990} A deficiency in branched-chain dehydrogenase, the enzyme that catabolizes valine, isoleucine, and leucine, leads to maple syrup urine disease, a disorder characterized by progressive ketoacidosis, failure to thrive, neurological dysfunction, and, potentially, death.{54328,60681}