Shelf life (days): 730.0
Formulation: A solution in water
Formal Name: 2',3'-dideoxy-guanosine 5'-(tetrahydrogen triphosphate), tetrasodium salt
Purity: ≥95%
Formula Markup: C10H12N5O12P3 / 4Na
Formula Weight: 579.109143
Notes: 2',3'-Dideoxyguanosine-5'-O-triphosphate (ddGTP) is a reverse transcriptase inhibitor (Kis = 13 and 6.7 nM for the visna virus and HIV-1 enzymes, respectively).{28268,28264} ddGTP has been used in the synthesis of oligonucleotides containing a terminal ddG that are resistant to cleavage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exonuclease.{67303} ddGTP has also been used to terminate chain extension produced by the Taq polymerase in PCR assays.{28266}