BAY-218, CAS 2162982-11-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 6-(4-chlorophenyl)-2-(3-fluorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-3-oxo-4-pyridazinecarboxamide

Purity: ≥98%

Formula Markup: C20H17ClFN3O3

Formula Weight: 401.818503

CAS Number: 2162982-11-6

Notes: BAY-218 is an aryl hydrocarbon receptor antagonist (AhR; IC50 = 39.9 nM).{64903} Preincubation with BAY-218 (1 µM) decreases AhR nuclear translocation induced by aflatoxin B1 (Item No. 11293) in L-02 hepatocytes and TK6 lymphoblasts.{64904} BAY-218 (30 mg/kg), alone and in combination with an anti-PD-L1 antibody, reduces tumor growth in a CT26 colorectal cancer mouse xenograft model.{64903}

• SKU: CAY37583-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37583-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe