C-DMG-mPEG(2000)

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: a-[3-[[[2,3-bis[(1-oxotetradecyl)oxy]propoxy]carbonyl]amino]propyl]-?-methoxy-poly(oxy-1,2-ethanediyl)

Purity: ≥95%

Formula Markup: (C2H4O)nC36H69NO7

Formula Weight: 0.0

Notes: PEG(2000)-C-DMG is a PEGylated derivative of 1,2-dimyristoyl-sn-glycerol (1,2-DMG; Item No. 15077).{64813} It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA. LNPs containing PEG(2000)-C-DMG and encapsulating siRNA targeting the genes encoding programmed cell death protein ligand 1 (PD-L1) and PD-L2 decrease PD-L1 and PD-L2 levels in monocyte-derived dendritic cells. Formulations containing PEG(2000)-C-DMG have been used in the development of LNPs for the delivery of siRNA-based vaccines.

• SKU: CAY37149-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37149-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe