PGS-IN-1, CAS 102271-49-8

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (E)-3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-2(3H)-furanone

Purity: ≥95%

Formula Markup: C19H26O3

Formula Weight: 302.40794

CAS Number: 102271-49-8

Notes: PGS-IN-1 is a non-steroidal anti-inflammatory drug (NSAID) and a dual inhibitor of COX and 5-lipoxygenase (5-LO; IC50s = 0.44 and 0.85 µM, respectively).{68317} It is selective for 5-LO over 12-LO (IC50 = >100 µM for the rabbit enzyme ). Oral administration of PGS-IN-1 (10 mg/kg per day) inhibits paw swelling and bone damage in a rat model of M. butyricum-induced arthritis.{68318}

• SKU: CAY37666-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37666-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe