Shelf life (days): 1460.0
Formulation: A solid
Formal Name: ?-[4-(trifluoromethyl)phenoxy]-benzenepropan-1,1,2,2,3-d5-amine, monohydrochloride
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C16H11D5F3NO / HCl
Formula Weight: 336.790529
CAS Number: 1185132-92-6
Notes: Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine (Item No. 15900) by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine.{25776} It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A.{25777} Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM).{25776} It has been found in the tissues of fish exposed to wastewater effluent.{62291}