Clone GMA-8002

Murine Anti-Factor VIII Clone GMA-8002
SKU
GMA8002-05
Packaging Unit
0,5 mg
Manufacturer
Green Mountain Antibodies

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Factor VIII (FVIII) is a heterodimer consisting of a heavy chain (ranging in mass from 90 to 200 kDa) bound via metal ions to a light chain (80 kDa). In plasma, FVIII circulates in an inactive form bound to von Willebrand factor. Following activation by factor Xa or thrombin, factor VIIIa can function as cofactor for the enzyme factor IXa in the activation of factor X in the presence of phospholipid and Ca2+. Absent or defective FVIII is the cause of the X-linked recessive bleeding disorder hemophilia A. GMA-8002 (also known as 2-116) recognizes the A1 domain of FVIII, and is suitable for bio-layer interferometry pairing and sandwich ELISA applications.
More Information
SKU GMA8002-05
Manufacturer Green Mountain Antibodies
Manufacturer SKU GMA-8002 0,5mg
Package Unit 0,5 mg
Quantity Unit STK
Reactivity Human, Dog (Canine)
Clonality Monoclonal
Application ELISA, Inhibition Assay
Isotype IgG2a
Host Mouse
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