PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt)

Shelf life (days): 1825.0

Formulation: A lyophilized powder

Formal Name: 1-(1,2-dihexadecanoyl(2,2’,3,3’,4,4’,5,5’,6,6’,7,7’,8,8’,9,9’,10,10’,11,11’,12,12’,13,13’,14,14’,15,16,16,16-d31)phosphatidyl)inositol-4,5-bisphosphate, trisodium salt

Purity: ≥99% deuterated forms (d1-d62)

Formula Markup: C41H16D62O19P3 / 3Na

Formula Weight: 1099.3

Notes: PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) is intended for use as an internal standard for the quantification of PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) (Item No. 10008115) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-4,5-P2-(1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns containing deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. This synthetic standard features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphatidylinositol 4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

• SKU: CAY10005615-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10005615-100
• Package Unit: 100 µg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung