Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2-(4,5-dihydroxyphenyl-2,3,6-d3)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C15H7D3O7 / XH2O
Formula Weight: 305.25388
Notes: Quercetin-d3(hydrate) is intended for use as an internal standard for the quantification of quercetin (Item No. 10005169) by GC- or LC-MS. Quercetin is an abundant flavonoid that has been isolated from a variety of plants and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.{36990,36991,36992} Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.{36991} It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days.{36990} Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.{36992}
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