Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-glycine, (phenyl-d5)methyl ester
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C21H18D5NO4S
Formula Weight: 390.50796
CAS Number: 1246815-11-1
Notes: Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril (Item No. 20390) by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan (Item No. 15600).{62164,62165} In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg, respectively.{62164} It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea.{62165} Formulations containing racecadotril have been used in the treatment of acute diarrhea.
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