Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2E-methyl-d3-4-(9H-purin-6-ylamino)-but-2-en-1,1-d2-1-ol
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C10H8D5N5O
Formula Weight: 224.27362
Notes: trans-Zeatin-d5 is intended for use as an internal standard for the quantification of trans-zeatin (Item No. 13226) by GC- or LC-MS. trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.{48717,48718,17848,48719} It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM.{17848} trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner.{48717} It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 µM.{48718} trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells.{48719} It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.