Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3',6'-dihydroxy-spiro[1H,3H-naphtho[1,8-cd]pyran-1,9'-[9H]xanthen-3-one
Purity: ≥98%
Formula Markup: C24H14O5
Formula Weight: 382.4
CAS Number: 41307-63-5
Notes: Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM).{16242} Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.{16242}