Product Description: Ricolinostat (ACY-1215) is a potent and selective HDAC6 inhibitor, with an IC50 of 5 nM. ACY-1215 also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 58, 48, and 51 nM, respectively.
Applications: Cancer-programmed cell death
Formula: C24H27N5O3
References: [1]Santo L, et al. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with PS-341 in multiple myeloma. Blood. 2012 Mar 15;119(11):2579-89.
CAS Number: 1316214-52-4
Molecular Weight: 433.50
Compound Purity: 99.83
Research Area: Cancer
Solubility: DMSO : ≥ 50 mg/mL
Target: Apoptosis;HDAC