Rilpivirine, CAS 500287-72-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]-benzonitrile

Purity: ≥98%

Formula Markup: C22H18N6

Formula Weight: 366.4

CAS Number: 500287-72-9

Notes: Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits growth of wild-type HIV with an EC50 value of 0.51 nM.{35241} It is active against NNRTI-resistant HIV strains with EC50 values less than 1 nM for L100I, K103N, V106A, G190A, and G190S mutants in vitro. Rilpivirine also reduces growth of greater than 80% of 1,500 NNRTI-resistant clinical isolates (EC50s = In vivo, rilpivirine, when used in combination with cabotegravir, lamivudine (Item No. 18514), and abcavir, reduces the plasma viral titer in HIV-1 infected humanized mice.{35242}

• SKU: CAY21559-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21559-5
• Package Unit: 5 mg
• Quantity Unit: STK