Riluzole, CAS 1744-22-5

Product Description: Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

Applications: Neuroscience-Neuromodulation

Formula: C8H5F3N2OS

References: [1]He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA(A) receptor function. Neuropharmacology. 2002 Feb;42(2):199-209./[2]Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51.

CAS Number: 1744-22-5

Molecular Weight: 234.202

Compound Purity: 99.80

Research Area: Neurological Disease; Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 1 mg/mL (ultrasonic;adjust pH to 3 with HCl)

Target: GABA Receptor;Sodium Channel

• SKU: MEXHY-B0211-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0211-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK