RIPK2 Inhibitor OD36 (hydrochloride), CAS 2387510-88-3

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (13Z)-25-chloro-14,15-dihydro-3,6-dioxa-9-aza-1(3,5)-pyrazolo[1,5-a]pyrimidina-2(1,3)-benzenacyclononaphane, monohydrochloride

Purity: ≥98%

Formula Markup: C16H15ClN4O2 / HCl

Formula Weight: 367.2

CAS Number: 2387510-88-3

Notes: A RIPK2 inhibitor (IC50 = 5.3 nM); inhibits wild-type and R206H mutant ALK2 (IC50s = 47 and 22 nM, respectively); inhibits activin A-induced chondrogenic and osteogenic differentiation in ATDC-5 cells overexpressing ALKR206H at 0.5 µM; reduces the number of peritoneal lavage neutrophils and lymphocytes in a mouse model of muramyl dipeptide-induced peritonitis at 6.25 mg/kg

• SKU: CAY42171-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42171-1
• Package Unit: 1 mg
• Quantity Unit: STK