Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-2,3,5,6-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C19H14ClD4N3O5S
Formula Weight: 439.9
CAS Number: 1132681-38-9
Notes: Rivaroxaban-d4 is intended for use as an internal standard for the quantification of rivaroxaban (Item No. 16043) by GC- or LC-MS. Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade.{25094} It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases. In various animal arterial and venous thrombosis models, rivaroxaban is reported to inhibit thrombin formation without prolonging bleeding time. Formulations containing rivaroxaban have been used as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms.{26130,26131}
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