RMC-4550, CAS 2172651-73-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]dec-8-yl]-6-(2,3-dichlorophenyl)-5-methyl-2-pyrazinemethanol

Purity: ≥98%

Formula Markup: C21H26Cl2N4O2

Formula Weight: 437.3623

CAS Number: 2172651-73-7

Notes: RMC-4550 is an inhibitor of Src homology region 2 domain-containing phosphatase 2 (SHP-2; IC50 = 1.55 nM).{58010} It is selective for SHP-2 over a panel of 14 additional protein phosphatases and a panel of 468 protein kinases at 10 µM. It inhibits tumor ERK phosphorylation in a KYSE-520 human esophageal cancer xenograft model in a dose-dependent manner.

• SKU: CAY31011-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 31011-10
• Package Unit: 10 mg
• Quantity Unit: STK