RN-1747, CAS 1024448-59-6

Product Description: RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1].

Applications: Neuroscience-Neuromodulation

Formula: C17H18ClN3O4S

References: [1]Vincent F, et al. Identification and characterization of novel TRPV4 modulators. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.

CAS Number: 1024448-59-6

Molecular Weight: 395.86

Compound Purity: 99.25

Research Area: Cardiovascular Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: TRP Channel

• SKU: MEXHY-19976-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19976-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK