RN-18, CAS 431980-38-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-(2-methoxyphenyl)-2-[(4-nitrophenyl)thio]-benzamide

Purity: ≥98%

Formula Markup: C20H16N2O4S

Formula Weight: 380.4

CAS Number: 431980-38-0

Notes: RN-18 is an inhibitor of HIV-1 viral infectivity factor (Vif), an HIV-1 regulatory protein that does not have cellular homologs.{40237} RN-18 inhibits Vif-mediated degradation of the DNA editing enzyme APOBEC3G with IC50 values of 10-30 µM in a high-throughput fluorescence screen. It inhibits viral replication of HIV-1 with IC50 values of 4.5 and 10 µM for nonpermissive CEM and H9 cells, respectively, and >100 µM for permissive cells.

• SKU: CAY23331-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23331-1
• Package Unit: 1 mg
• Quantity Unit: STK