Ro 20-1724 (Standard), CAS 29925-17-5

Product Description: Ro 20-1724 (Standard) is the analytical standard of Ro 20-1724. This product is intended for research and analytical applications. Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect[1][2].

Formula: C15H22N2O3

References: [2]Sharma V, et al. Neuroprotective effect of RO-20-1724-a phosphodiesterase4 inhibitor against intracerebroventricular streptozotocin induced cognitive deficit and oxidative stress in rats. Pharmacol Biochem Behav. 2012;101(2):239-245./[1]Brackeen MF, et al. Design and synthesis of conformationally constrained analogues of 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as potent inhibitors of cAMP-specific phosphodiesterase. J Med Chem. 1995;38(24):4848-4854.

CAS Number: 29925-17-5

Molecular Weight: 278.35

Research Area: Neurological Disease

Target: Phosphodiesterase (PDE);Reference Standards

• SKU: MEXHY-100927R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100927R-0
• Package Unit: Get quote
• Quantity Unit: STK