Ro 25-6981 (maleate), CAS 1312991-76-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: aR-(4-hydroxyphenyl)-ßS-methyl-4-(phenylmethyl)-1-piperidinepropanol, 2Z-butenedioate

Purity: ≥95%

Formula Markup: C22H29NO2 / C4H4O4

Formula Weight: 455.6

CAS Number: 1312991-76-6

Notes: Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively).{22852} Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons against glutamate toxicity and combined oxygen and glucose deprivation with IC50 values of 0.4 and 0.04 μM, respectively.{22852}

• SKU: CAY14578-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14578-10
• Package Unit: 10 mg
• Quantity Unit: STK